hiv 1 inhibitor 3 — TargetMol Chemicals

Cat No.	Product Name	Synonyms	Targets
T11564	HIV-1 inhibitor-3		Others
	HIV-1 inhibitor-3 is an HIV infection inhibitor.		Others
T11567	HIV-1 integrase inhibitor 3		Others
	HIV-1 integrase inhibitor 3 is an HIV-1 integrase strand transfer (INST) inhibitor (IC50: 2.7 nM).		Others
T9854	HIV-1 inhibitor-6	3-Pyridinecarboxamide, 1,4-dihydro-1-methyl-N-(5-nitro-1,2-benzisothiazol-3-yl)-4-oxo-	HIV Protease
	HIV-1 inhibitor-6 (3-Pyridinecarboxamide, 1,4-dihydro-1-methyl-N-(5-nitro-1,2-benzisothiazol-3-yl)-4-oxo-) is a potent HIV-1 pre-mRNA selective splicing inhibitor that blocks HIV replication.		HIV Protease
T11074	Dolutegravir intermediate-1	1-(2,2-dimethoxyethyl)-5-methoxy-6-methoxycarbonyl-4-oxopyridine-3-carboxylic acid,1-(2,2-dimethoxyethyl)-5-methoxy-6-(methoxycarbonyl)-4-oxo-1,4-dihydropyridine-3-carboxylic acid	HIV Protease
	Dolutegravir intermediate-1 (1-(2,2-dimethoxyethyl)-5-methoxy-6-(methoxycarbonyl)-4-oxo-1,4-dihydropyridine-3-carboxylic acid) is a new synthetic Dolutegravir intermediate. Dolutegravir is an integrase inhibitor develope...		HIV Protease
T7700	Lersivirine	Lersivirine(UK 453061),UK-453061	HIV Protease , Reverse Transcriptase
	Lersivirine (UK-453061)(UK 453061) is a second-generation non-nucleoside reverse transcriptase inhibitor (NNRTI) under development for HIV infection therapy.		HIV Protease , Reverse Transcriptase
T6418	BMS-378806	BMS378806,BMS-806	gp120/CD4 , HIV Protease
	BMS-378806 (BMS-806) selectively inhibits the binding of HIV-1 gp120 to the CD4 receptor with EC50 of 0.85-26.5 nM in virus.		gp120/CD4 , HIV Protease
T5949	Dideoxyadenosine
	2',3'-Dideoxyadenosine is an inhibitor of HIV replication with antiretroviral activity and antiviral efficacy [1].
T10133	3'-Azido-3'-deoxy-5-methylcytidine		Antiviral , HIV Protease
	3'-Azido-3'-deoxy-5-methylcytidine inhibits HIV-1 reverse transcriptase(EC50 = 0.06 μM) and is an effective inhibitor of xenotropic murine leukemia-related retrovirus (XMRV, CC50 = 43.5 μM).		Antiviral , HIV Protease
T0682	Lamivudine	GR109714X,BCH-189	HIV Protease , Reverse Transcriptase
	Lamivudine (BCH-189) is a reverse transcriptase inhibitor and ZALCITABINE analog in which a sulfur atom replaces the 3' carbon of the pentose ring. It is used to treat HIV disease.		HIV Protease , Reverse Transcriptase
T14313	Apricitabine	AVX754,SPD754	HIV Protease , DNA/RNA Synthesis
	Apricitabine (SPD754) is a highly selective and orally active HIV-1 reverse transcriptase inhibitor (Ki=0.08 μM), the (-) enantiomer of 2′-deoxy-3′-oxy-4′-thiocytidine (dOTC) . Apricitabine inhibits DNA polymerase α, β a...		HIV Protease , DNA/RNA Synthesis
T2279	Tizoxanide	Desacetyl-nitazoxanide,TIZ	Antiviral , HIV Protease , Antibacterial , Autophagy
	Tizoxanide (Desacetyl-nitazoxanide) is a metabolite of lamivudine. Lamivudine (2', 3'-dideoxy-3'-thiacytidine, commonly called 3TC) is a potent nucleoside analog reverse transcriptase inhibitor (nRTI).		Antiviral , HIV Protease , Antibacterial , Autophagy
T10603	BRD-6929		HIV Protease , HDAC
	BRD-6929 is a selective, brain-penetrant HDAC1 and HDAC2 inhibitor (IC50: 1 and 8 nM). BRD-6929 (Cpd-60) shows high-affinity to HDAC1 and HDAC2 (Kis: 0.2 and 1.5 nM) [2]. BRD-6929 potentiates the efficacy of gnidimacrin...		HIV Protease , HDAC
T16791	Rottlerin	Mallotoxin,NSC 56346,NSC 94525	CaMK , Apoptosis , Others , HIV Protease , PKA , PKC , Autophagy
	Rottlerin (NSC-56346) is a natural product purified from Mallotus Philippinensis and is a specific PKC inhibitor (IC50: PKCδ of 3-6 μM, PKCα,β,γ of 30-42 μM, PKCε,η,ζ of 80-100 μM). Rottlerin causes apoptosis via caspase...
T24266	KNI-1657
	KNI-1657 is a potent and selective HIV-1 protease inhibitor (Anti-HIV-1 pNL4-3, EC50: 3 nM). KNI-1657 is a highly potent HIV-1 Protease Inhibitor against Lopinavir.
T64131	HIV-1 inhibitor-17
	HIV-1 inhibitor-18 is a potent inhibitor of the HIV-1 capsid and is able to act on the HIV-1 NL4-3 strain (EC50: 2.57 μM). HIV-1 inhibitor-18 exhibits some cytotoxicity with an MT-4CC50 value of >8.55.
T63687	HIV-1 inhibitor-18
	HIV-1 inhibitor-18 is a potent inhibitor of the HIV-1 capsid that acts against the HIV-1 NL4-3 strain (EC50: 5.14 μM) and exhibits some cytotoxicity (MT-4CC50>9.51).
T72162	HIV-1 integrase inhibitor 10
	HIV-1 Integrase Inhibitor 10, an orally active allosteric integrase inhibitor (ALLINI), effectively inhibits the NLRepRluc virus's viral outgrowth in MT-2 cells, exhibiting EC50 values of 3-5 nM. This compound is utilize...
T10986	DDX3-IN-1		Others
	DDX3-IN-1 is a DEAD-box polypeptide 3 (DDX3) inhibitor with CC50 of 50 and 36 μM for HIV and HCV, respectively. Antiviral activity.		Others
T60342	HIV-1 inhibitor-47
	HIV-1 inhibitor-47 is a compound that effectively inhibits HIV-1 by preventing the vif-dependent degradation of human APOBEC3G. It has a notable inhibition effect, with an IC50 value of 14.33 μM. Additionally, HIV-1 inhi...
TNU0208	2’,3’-Dideoxy-3’-fluorocytidine
	Nucleoside Derivatives - 2’,3’-Dideoxy-nucleosides, Fluoro-modified nucleosides, 3’-Modified nucleosides; Drugs and Inhibitors; HIV-1 inhibitor